High-Throughput Sequencing Initiative Research Projects

     

IFSH High Throughput Sequencing Topics of Investigation

  • Foodborne bacterial community composition and its transitional stages in the cycle of production, processing, packaging, storage, distribution and consumption of different foods
  • Mapping the biogeography of foodborne bacterial communities in crop and animal farms
  • Human gut microbiome and its changes in response to the dietary regimes of interest
  • Toxin production and regulation in model bacteria including Clostridium botulinum
  • Rapid and reliable identification of foodborne microorganisms including bacteria, viruses, and eukaryotic microbes of interest
  • Bacterial resistance against antibiotics, sanitizers, disinfectants, heat, cold and pressure
  • Evolution of pathogenicity in foodborne bacteria

IFSH High Throughput Sequencing Research Projects

  • Investigating the possible mutagenic effects of manipulating the treatment time, frequency, energy and voltage on a Pulsed Light instrument in the genome of Listeria monocytogenes
  • Evaluating the use of Whole Genome Sequencing (WGS) in linking contaminated seed to sprout in recent Salmonella outbreaks
  • Characterization of more than 100 Group I and Group II Clostridium botulinum strains with a focus on toxin gene clusters
  • Identifying the genes involved in the regulation of botulinum neurotoxin production, using transcriptomics (RNA-seq) of Clostridium botulinum, investigating the role of growth media, pH and temperature
  • Investigating microbial community composition and characterization of transitional stages of this community in conjunction with the biofilm formation in an industrial setting
  • Investigating the effects of select sanitizers on the structure and composition of microbial community in various industrial and laboratory settings
  • Characterization and comparison of soil microbial communities in Detroit city community gardens 

HTS Services And Facilities

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HTS Symposiums And Presentation Materials

The IHI is also active in educational events and training programs. Since its start in 2016, the IHI has organized the following HTS symposiums:

         

Key Staff Members And Contact Information 

Behzad Imanian, Ph.D.

Research Assistant Professor, Leader of IFSH High Throughput Sequencing, IIT
708-563-8171

Melissa Widel

Support Scientist, IIT
708-563-2052
  

Membership Application Process

ARMAND PARADIS

Director Business Development
708.563.8175 (office)
708.821.8615 (mobile)
 

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